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KMID : 0383820130750010028
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Tuberculosis and Respiratory Diseases
2013 Volume.75 No. 1 p.28 ~ p.31
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Mycobacterium intracellulare Pulmonary Disease with Endobronchial Caseation in a Patient Treated with Methotrexate
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Park Jin-Sun
Jung Eul-Sik
Choi Woo-Suk
Park Soo-Yong
Rim Min-Young
Yu In-Ku
Park Hyeon-Su
Lee Sang-Min
Park Jeong-Woong
Jeong Sung-Hwan
Lee Sang-Pyo
Park Sang-Hui
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Abstract
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Methotrexate (MTX) has been established as a standard disease-modifying anti-rheumatic drug. If adequate disease control is achieved for a reasonable period of time, tapering the MTX dosage is recommended because the chronic use of MTX can result in opportunistic infection. We present here a case of a woman with rheumatoid arthritis taking MTX, and the woman developed actively caseating endobronchial Mycobacterium intracellulare disease with pulmonary infiltrations. After discontinuing the MTX, the patient was able to tolerate 18 months of antimycobacterial treatment without flare ups of rheumatoid arthritis, and she completely recovered from nontuberculous mycobacterial respiratory disease.
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KEYWORD
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Nontuberculous Mycobacteria, Tuberculosis, Pulmonary, Methotrexate, Arthiritis, Rheumatoid, Bronchial Diseases
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